Skip to main content

Table 1 Peak intensity ratios of 1H NMR spectra obtained from A549 and A549/DDP cells treated with 30 μM cisplatin and cultured for 0 h, 24 h, and 48 h.

From: NMR studies of the relationship between the changes of membrane lipids and the cisplatin-resistance of A549/DDP cells

Cells

Treated time

CH2/CH3

Chol/CH3

Glu/Ct

Eth/Ct

Ino/Ct

A549

0 hrs

3.63 ± 0.08

0.26 ± 0.06

4.11 ± 0.15

0.56 ± 0.05

0.23 ± 0.07

 

24 hrs

4.12 ± 0.09

0.19 ± 0.05

4.39 ± 0.18

0.41 ± 0.06

0.16 ± 0.06

 

48 hrs

4.25 ± 0.06

0.11 ± 0.06

4.94 ± 0.12

0.33 ± 0.05

0.12 ± 0.08

A549/DDP

0 hrs

2.21 ± 0.09

0.28 ± 0.06

3.66 ± 0.27

0.68 ± 0.04

0.25 ± 0.04

 

24 hrs

2.04 ± 0.06

0.33 ± 0.04

3.62 ± 0.16

0.74 ± 0.06

0.29 ± 0.08

 

48 hrs

1.66 ± 0.08

0.39 ± 0.09

3.60 ± 0.03

0.86 ± 0.05

0.33 ± 0.06

  1. Data represent mean values ± SD (n = 3). P < 0.05.