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Table 1 Peak intensity ratios of 1H NMR spectra obtained from A549 and A549/DDP cells treated with 30 μM cisplatin and cultured for 0 h, 24 h, and 48 h.

From: NMR studies of the relationship between the changes of membrane lipids and the cisplatin-resistance of A549/DDP cells

Cells Treated time CH2/CH3 Chol/CH3 Glu/Ct Eth/Ct Ino/Ct
A549 0 hrs 3.63 ± 0.08 0.26 ± 0.06 4.11 ± 0.15 0.56 ± 0.05 0.23 ± 0.07
  24 hrs 4.12 ± 0.09 0.19 ± 0.05 4.39 ± 0.18 0.41 ± 0.06 0.16 ± 0.06
  48 hrs 4.25 ± 0.06 0.11 ± 0.06 4.94 ± 0.12 0.33 ± 0.05 0.12 ± 0.08
A549/DDP 0 hrs 2.21 ± 0.09 0.28 ± 0.06 3.66 ± 0.27 0.68 ± 0.04 0.25 ± 0.04
  24 hrs 2.04 ± 0.06 0.33 ± 0.04 3.62 ± 0.16 0.74 ± 0.06 0.29 ± 0.08
  48 hrs 1.66 ± 0.08 0.39 ± 0.09 3.60 ± 0.03 0.86 ± 0.05 0.33 ± 0.06
  1. Data represent mean values ± SD (n = 3). P < 0.05.