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Table 2 Comparison of the concentration of phosphorus metabolites per 5 × 108 cells at 22°C for A549 and A549/DDP cells

From: NMR studies of the relationship between the changes of membrane lipids and the cisplatin-resistance of A549/DDP cells

Cells

Treated time

PME/Ref

γ-ATP/Ref

α-ATP+NAD/Ref

β-ATP/Ref

A549

0 hrs

1.90 ± 0.12

0.76 ± 0.06

1.10 ± 0.05

0.47 ± 0.05

 

24 hrs

1.25 ± 0.11

0.45 ± 0.05

0.74 ± 0.05

0.34 ± 0.04

 

48 hrs

1.02 ± 0.18

0.34 ± 0.08

0.65 ± 0.12

0.28 ± 0.05

A549/DDP

0 hrs

0.86 ± 0.04

0.57 ± 0.06

0.60 ± 0.05

0.51 ± 0.05

 

24 hrs

1.04 ± 0.06

0.60 ± 0.05

0.74 ± 0.08

0.58 ± 0.04

 

48 hrs

1.25 ± 0.08

0.67 ± 0.06

0.87 ± 0.12

0.64 ± 0.05

  1. Data represent mean values ± SD (n = 3). P < 0.05.