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Figure 3 | Cancer Cell International

Figure 3

From: Possible role of membrane gamma-glutamyltransferase activity in the facilitation of transferrin-dependent and -independent iron uptake by cancer cells.

Figure 3

Effects of GGT inhibition on transferrin-bound iron uptake in K562 cells. Online fluorimetric monitoring of intracellular iron levels. Transferrin (>70% iron-saturated) was added where indicated, and the decrease in fluorescence of intracellular calcein was recorded (cfr. Methods for details of the procedure). One representative experiment out of five is reported.

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