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Figure 9 | Cancer Cell International

Figure 9

From: Potential mechanism of phytochemical-induced apoptosis in human prostate adenocarcinoma cells: Therapeutic synergy in genistein and β-lapachone combination treatment

Figure 9

CPP32 is the major pathway in genistein-induced apoptosis in PC3 cells. PC3 cells (2.5 × 103 cells/well) were cultured in 48-well culture plates; treated with/without 100 μM caspase inhibitor (zVAD-fmk) for 2 hr; then with 1–8 μM β-Lapachone (bLap) for 4 hr as described in the methods. Cells were then analyzed for caspase (CPP32) activity and corresponding apoptosis. Data pointsare the means ± SEM of two independent experiments performed in triplicates

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Cancer Cell International

ISSN: 1475-2867

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