Therapy Group | n | WBC × 103/μL | RBC × 106/μL | Platelets × 103/μL | Micronuclei (%RBC) |
---|
Early Kill1 | | | | | |
n-6 | 4 | 2.91 ± 0.83 | 9.08 ± 0.07 | 584 ± 76 | 1.3 ± 0.04 |
n-6/IR | 4 | 0.11 ± 0.01 | 7.50 ± 0.16 | 389 ± 17 | 1.2 ± 0.03 |
n-3 | 7 | 2.02 ± 0.30 | 8.45 ± 0.12 | 634 ± 51 | 1.2 ± 0.03 |
n-3/IR | 4 | 0.16 ± 0.03 | 7.66 ± 0.07 | 358 ± 78 | 1.5 ± 0.04 |
Late Kill2 | | | | | |
n-6 | 8 | 1.85 ± 0.37 | 8.30 ± 0.14 | 551 ± 83 | 1.6 ± 0.06 |
n-6/IR | 13 | 1.48 ± 0.32 | 7.06 ± 0.16 | 973 ± 98 | 1.1 ± 0.01 |
n-3 | 16 | 2.85 ± 0.42 | 8.31 ± 0.20 | 582 ± 61 | 1.3 ± 0.04 |
n-3/IR | 10 | 0.92 ± 0.18 | 6.10 ± 0.40 | 918 ± 131 | 0.9 ± 0.03 |
- 1Mice euthanized one day after last irradiation treatment.
- 2Mice euthanized 22 days after last irradiation treatment.
- Results of Statistical Analyses:
- 1. At one day after the end of irradiation therapy, there were significant decreases in WBC, RBC, and platelet counts due to the irradiation. There were no other significant differences at p < 0.01.
- 2. At 22 days after the end of irradiation therapy, WBC and RBC counts were still significantly decreased and there was a significant increase in platelet counts due to irradiation. There were no other significant differences at p < 0.01.