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Figure 4 | Cancer Cell International

Figure 4

From: U94 alters FN1 and ANGPTL4 gene expression and inhibits tumorigenesis of prostate cancer cell line PC3

Figure 4

Upregulated genes in PC3 cell line stably expressing U94. Two clones of G418 resistant PC3 cell lines transfected with plasmid pBk-U94 (tests 1 and 2) and a clone transfected with plasmid pBK-CMV (reference) were used for cDNA microarray studies. Each experiment was performed in triplicate and the results are mean ± SD. Notice the dramatic upregulation of FN 1 (91 ± 16-fold). A subset of other genes was also upregulated, but genes of interest in this study (> 6-fold change) include: SERPINE 2 (7 ± 1-fold); and ADAMTS 1 (7 ± 2-fold).

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Cancer Cell International

ISSN: 1475-2867

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