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Table 1 Amino acid sequences of Pep27 derived from S. pneumoniae and its analogue peptides, and their retention times

From: Functional and structural characteristics of anticancer peptide Pep27 analogues

Peptide Amino acid sequences Remarks (substitution) RT (min)
Pep27 MRKEFHNVLSSGQLLADKRPARDYNRK (2R→W), (4E→W) 14.54
Pep27anal1 MWKWFHNVLSSWQLLADKRPARDYNRK (2R→W), (4E→W) 18.67
Pep27anal2 MWKWFHNVLSWWWLLADKRPARDYNRK (2R→W), (4E→W), (11S→W), (13Q→W) 22.50
Pep27anal3 MRKWFHNVLSSGQLLADKWPAWDYNRK (4E→W), (19R→W), (22R→W), (26R→W) 20.08
Pep27anal4 MWKEFHNVLSSGQLLADKRWARWYNRW (2R→W), (20P→W), (23D→W), (27K→W) 19.15
Pep27anal5 MWKWFHNVLSSGQLLADKWWAWWYNWW (2R→W), (4E→W), (19R→W), (20P→W), (22R→W), (23D→W), (26R→W), (27K→W) 19.17
  1. RT, retention time obtained by RP-HPLC