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Table 2 Anticancer activity of Pep27 and of its analogues in various cancer cell lines by MTT assay

From: Functional and structural characteristics of anticancer peptide Pep27 analogues

Peptide IC50 (μM)
  AML-2 HL-60 Jurkat SNU-601 MCF-7
Pep27 >70 >70 >70 >70 >70
Pep27anal1 50 53 47 37 55
Pep27anal2 29 20 23 25 <10
Pep27anal3 67 52 50 50 38
Pep27anal4 50 51 46 37 29
Pep27anal5 >70 >70 >70 >70 >70
  1. AML-2, acute myelogenous leukemia cell line; HL-60, acute promyelocytic leukemia cell line; Jurkat, T cell leukemia cell line; SNU-601, gastric cancer cell line; MCF-7, breast cancer cell line