Table 2 Anticancer activity of Pep27 and of its analogues in various cancer cell lines by MTT assay
From: Functional and structural characteristics of anticancer peptide Pep27 analogues
Peptide | IC50 (μM) | ||||
|---|---|---|---|---|---|
AML-2 | HL-60 | Jurkat | SNU-601 | MCF-7 | |
Pep27 | >70 | >70 | >70 | >70 | >70 |
Pep27anal1 | 50 | 53 | 47 | 37 | 55 |
Pep27anal2 | 29 | 20 | 23 | 25 | <10 |
Pep27anal3 | 67 | 52 | 50 | 50 | 38 |
Pep27anal4 | 50 | 51 | 46 | 37 | 29 |
Pep27anal5 | >70 | >70 | >70 | >70 | >70 |