Figure 4

Effect of DL-Buthionine (S,R)-sulfoximine (BSO) on vincristine cytotoxicity and survival promoting effect of N-acetylcysteine (NAC) in human embryonic kidney (HEK293) and 293MRP Cells. * p < 0.05 vs HEK293 cells pretreated with BSO ** p < 0.05 vs 293MRP cells pretreated with BSO *** p < 0.05 vs HEK293 cells treated with Vinc † p < 0.05 vs 293MRP cells treated with Vinc †† p < 0.05 vs HEK293 cells treated with BSO+Vinc and HEK293 cells treated with Vinc ††† p < 0.05 vs 293MRP cells treated with BSO+Vinc ‡ p < 0.05 vs 293MRP cells treated with BSO+Vinc+1 mM NAC ‡‡ p < 0.05 vs HEK293 cells treated with BSO+Vinc+1 mM NAC.