Figure 4

Taxotere chemosensitivity effect is compared on SQ images of pre- and post Taxotere treatment (first vs second rows on top). Panel on second row on rightmost image, represents the tumor SQ image (left arrow) and phantom (right arrow). Third and fourth rows represent the panels showing contrast (arrows) on contiguous intracellular sodium MRI images as "IR" images of pre- and post Taxotere treatment respectively by inversion recovery method. Panels in fifth and sixth rows represent the intracellular sodium signal intensity increases (arrows) in some areas representing active proliferation or resting viable cells. Loss of signal in late apoptosis rich regions and increased tumor areas can be seen as hypointense areas (panels in fifth row vs sixth row for pre- and post-injection of taxotere). An enlarged "IR" image (panel in sixth row) of tumor (on rightmost insert A) after segmentation image processing is shown with different bright, gray and darker pixel signal intensities.