Figure 1

Putative structure of HPV-16 E5. Cartoon representation of the averaged results of multiple secondary structure predictions of reference sequence of HPV-16 E5 protein [25, 26] (e.g. using programmes at http://pref.etfos.hr/split/: data not shown) showing the position of the predicted α-helices, the proposed voltage gating motif, as well as the amino-acid mutations of the natural variants studied.