Table 2 Sequence analysis of PDGFRα exons 12 and 18 from eight primary cervical cancer cell lines.
CELL LINE | EXON 12 | EXON 18 | ||||||
|---|---|---|---|---|---|---|---|---|
localization | change | position | amino acid | localization | change | position | amino acid | |
ViBo | Exon | G>A CCA >CCG | Codon 567 | Pro > Pro | Intron | C >G | IVS18 +21 | --- |
Exon | G>A CCA >CCG | Codon 577 | Pro > Pro | Intron | A >G | IVS18 +25 | --- | |
Exon | A>G TCA >TCG | Codon 584 | Ser > Ser | ----- | ||||
Intron | A> G | IVS12 +17 | ---- | ----- | ||||
Intron | T> C | IVS12 +35 | ---- | ----- | ||||
ViPa | WT | Exon | C >T GTC>GTT | Codon 824 | Val > Val | |||
HeLa | WT | Exon | C >T GTC>GTT | Codon 824 | Val > Val | |||
CaLo | WT | Exon | C >T GTC>GTT | Codon 824 | Val > Val | |||
INBL | WT | Exon | C >T GTC>GTT | Codon 824 | Val > Val | |||
C33 | Exon | G >A GAA>AAA | Codon 571 | Glu > Lys | WT | |||
Caski | Exon | G >A GAA>AAA | Codon 571 | Glu > Lys | WT | |||
SiHa | Exon | G >A GAA>AAA | Codon 571 | Glu > Lys | WT | |||