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Table 1 Mutations in lung compared to all cancers (including lung) in p53 codons 210–290

From: Mechanisms of genotoxin-induced transcription and hypermutation in p53

  A C G T
Total number of all mutations in 240 nt (6662) 865 1875 3375 547
Percent of total 13.0% 28.1% 50.7% 8.2%
Number of lung mutations in 240 nt (875) 126 198 484 67
Percent of lung 14.4% 22.6% 55.3% 7.7%
Difference in total mutations compared to lung mutations +1.4% -5.5% +4.6% -0.5%
  1. All point mutations in codons 210–290 were analyzed.
  2. Table 1 shows the total number of all mutations (including lung) compared to lung mutations and the propensity of each of the four bases to mutate to any other base. This sequence is composed of 56 As, 66 Cs, 67 Gs, and 54 Ts. Mutations of G are shown in bold.