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Table 6 Mutations of C to other bases in p53 codons 210–290

From: Mechanisms of genotoxin-induced transcription and hypermutation in p53

  A G T
Total C mutations including colon (1875) 157 187 1531
Percent of total 8.4% 10.0% 81.6%
Colon C mutations (260) 8 10 242
Percent of colon 3.1% 3.8% 93.1%
Difference in total C mutations due to the presence of colon C mutations -5.3% -6.2% +11.5%
  1. Analyzed as in Tables 1-3 for colon cancer.
  2. Table 6 shows the ultimate fate of C mutations in all types of cancers due to the presence of colon cancers.