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Table 6 Mutations of C to other bases in p53 codons 210–290

From: Mechanisms of genotoxin-induced transcription and hypermutation in p53

 

A

G

T

Total C mutations including colon (1875)

157

187

1531

Percent of total

8.4%

10.0%

81.6%

Colon C mutations (260)

8

10

242

Percent of colon

3.1%

3.8%

93.1%

Difference in total C mutations due to the presence of colon C mutations

-5.3%

-6.2%

+11.5%

  1. Analyzed as in Tables 1-3 for colon cancer.
  2. Table 6 shows the ultimate fate of C mutations in all types of cancers due to the presence of colon cancers.