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Figure 3 | Cancer Cell International

Figure 3

From: HIF-2α downregulation in the absence of functional VHL is not sufficient for renal cell differentiation

Figure 3

Knockdown of HIF-2α has only a slight effect on cell morphology. (A) Parental 786-O cells (786-O), 786-O cells stably transfected with VHL (VHL +), and 786-O cells infected with an empty retrovirus (pSuperRetro) or doubly infected with both HIF-2α shRNAs (HIF2α shRNA) were grown for 4 days on thin layers of collagen I. Images were captured by digital camera mounted on an inverted microscope. (B) Morphological analysis was performed as in (A) using A498 cell lines grown for 7 days on thin layers of collagen I.

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Cancer Cell International

ISSN: 1475-2867

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