Release of volatile organic compounds (VOCs) from the lung cancer cell line CALU-1 in vitro

Table 2 Quantification of VOCs released from CALU-1 cancer cells after adsorption on solid sorbents with subsequent TD-GC-MS analyses.

				Concentration [ppb_v] after 18 hours of incubation						mean ppb Medium	mean ppb Cells	ppb Cells/ppb Medium
Compound	CAS	R²	LOD [ppb_v]	Medium			Cells
2,3,3-trimethylpentane	560-21-4	0,998	0,127	0,37	0,45	0,40	0,60	0,84	0,86	0,41	0,77	1,89
2,3,5-trimethylhexane	1069-53-0	0,997	0,149	0,43	0,42	0,29	0,79	0,67	0,50	0,38	0,65	1,71
2,4-dimethylheptane	2213-23-2	0,996	0,179	0,33	0,35	0,20	1,25	0,77	0,65	0,29	0,89	3,04
4-methyloctane	2216-34-4	0,985	1,168	1,33	1,51	2,02	4,03	2,09	2,17	1,62	2,76	1,71

The concentrations of these VOCs are increased in headspace of CALU-1 cells in comparison with medium only, after 18 hours of incubation. The concentrations of discussed VOCs are given for each measured sample (headspace of CALU-1 cells and of medium). The correlation coefficients (for calibration experiments) and the limits of detection (LODs) are presented.

ISSN: 1475-2867