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Table 2 Analyses of overall PSA relapse*.

From: Ebp1 expression in benign and malignant prostate

 

Univariate analyses†

 

Normal adjacent expression

Tumor expression

 

Hazard ratio (95% CI);

Hazard ratio (95% CI);

 

p-value

p-value

 

Cut-off (median)‡

Cut-off (median)‡

Ebpl

1.75(0.79–3.89);

1.15(0.58–2.26);

 

p = 0.170

p = 0.689

 

Median = 2.00

Median = 2.50

Androgen Receptor

0.48 ((0.24–0.95);

0.51 (0.25–1.02);

 

p = 0.035

p = 0.056

 

Median = 61.25

Median = 81.67

Cyclin D1

0.34(0.17–0.69);

0.57(0.29–1.14);

 

p = 0.002

p = 0.113

 

Median = 2.50

Median = 14,38

ErbB3

0.42 (0.21–0.85);

1.16(0.59–2.29);

 

p = 0.016

p = 0.665

 

Median = 3.75

Median = 5.63

Ki67

1.03 (0.52–2.04);

1.01 (0,52–1,96);

 

p = 0.936

p = 0.976

 

Median = 29.50

Median = 127.25

  1. Correlation between PSA relapse and the expression of the five molecular marker expression in normal adjacent and tumor tissues using univariate Cox regression analyses. The median value used as the statistical cut-off is also shown.
  2. * Data was categorized according to the median.
  3. †Univariate COX regression with the "ENTER" model
  4. ‡Median expression was used as cut-offs for catergorized data.
  5. Bold indicates statistically significant values
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Cancer Cell International

ISSN: 1475-2867

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