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Table 4 Univariate and multivariate Cox regression analyses of PSA relapse.

From: Ebp1 expression in benign and malignant prostate

 

Univariate analyses

Multivariate analyses

  

Base model

Base model + CyclinD1+/ErbB3+(T)

Base model + Ebp1+/CyclinD1-(T)

 

Hazard ratio (95% CI); p

Hazard ratio (95% CI); p

Hazard ratio (95%CI); p

Hazard ratio (95%CI); p

Gleason < 7 vs Gleason 7

1.67

0.99

0.96

1.36

 

(0.78–3.57);

(0.45–2.19);

(0.43–2.17);

(0.58–3.20);

 

p = 0.186

p = 0.977

p = 0.924

p = 0.484

Gleason < 7 vs Gleason > 7

2.80

4.21

5.75

6.80

 

(1.15–6.81);

(1.65–10.75):

(2.14–15.44);

(2.40–19.30):

 

p = 0.023

p = 0.030

p < 0.001

p < 0.001

Pre-Op PSA

1.03

..

..

..

 

(0.99–1.07);

..

..

..

 

p = 0.198

..

..

..

Surgical Margins

5.97

8.06

9.91

12.06

 

(2.68–13.3);

(3.32–19.55);

(3.96–24.81);

(4.48–32.49);

 

p < 0.001

p < 0.001

p < 0.001

p < 0.001

P-Stage

5.15

..

..

..

 

(2.49–10.63);

..

..

..

 

p < 0.001

..

..

..

Molecular Marker

..

..

0.44

4.79

 

..

..

(0.20–0.94);

(1.73–13.26);

 

..

..

p = 0.034

p = 0.003

Model P value

..

p < 0.001

p < 0.001

p < 0.001

  1. Correlation between PSA relapse and the clinico-pathological parameters using univariate Cox regression analyses. Multi-variate Cox regression analysis of the base models and the base model + molecular marker.
  2. * Multi-Variate COX regression was perform under the Forward Wald model
  3. Normal Adjacent Tissues (NA): Tumor Tissues (T)
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Cancer Cell International

ISSN: 1475-2867

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