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Figure 3 | Cancer Cell International

Figure 3

From: Lack of c-kit receptor promotes mammary tumors in N-nitrosomethylurea-treated Ws/Ws rats

Figure 3

Immunostaining for c-kit. Panels A and B: c-kit is expressed in the cytoplasm of luminal epithelial cells (arrows) and mast cells (arrowhead) present in the stroma of control F344 and wild type rat mammary glands. Panel C: c-kit is not expressed in a mammary tumor obtained from a control F344 rat. Panel D: as expected, Ws/Ws rats do not express c-kit. Counterstaining: Harris' hematoxylin. Ws/Ws: c-kit null rats. Scale bar: 50 μm

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