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Figure 1 | Cancer Cell International

Figure 1

From: Inter-cellular adhesion disruption and the RAS/RAF and beta-catenin signalling in lung cancer progression

Figure 1

Epithelial cell types in the distal mouse lung. Epithelial cell types present in the distal lung that might be target cells for oncogenic transformation are the bronchio-alveolar stem cell (BASC) that localizes to the bronchio-alveolar duct junction (BADJ) and more differentiated cells with specific functions such as type II pneumocytes and Clara cells. The cuboidal alveolar type II cells as well as the columnar Clara cell may assume progenitor cell status in case of injury. Whether terminally differentiated type I pneumocytes can be recruited into tumours is not known.

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Cancer Cell International

ISSN: 1475-2867

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