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Figure 5 | Cancer Cell International

Figure 5

From: A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumors

Figure 5

Rat brain organotypic slice can support stem cell survival and migration toward human tumor cells. A: Part of rat brain slice showing the implantation site (arrow) of GFP labeled neural stem cells (NSC) (phase contrast, 4×). B: Same field as (A) under fluorescence illumination showing the implanted cells (arrow). C: As early as 1 hour of implantation, NSC migrated out of the initial site toward a remotely implanted brain tumor site (not shown); D Live imaging of NSC 30 days after implantation indicating that NSC survived at least 30 days on the slice (40×).

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Cancer Cell International

ISSN: 1475-2867

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