Figure 5From: A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumorsRat brain organotypic slice can support stem cell survival and migration toward human tumor cells. A: Part of rat brain slice showing the implantation site (arrow) of GFP labeled neural stem cells (NSC) (phase contrast, 4×). B: Same field as (A) under fluorescence illumination showing the implanted cells (arrow). C: As early as 1 hour of implantation, NSC migrated out of the initial site toward a remotely implanted brain tumor site (not shown); D Live imaging of NSC 30 days after implantation indicating that NSC survived at least 30 days on the slice (40×).Back to article page