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Table 1 Comparison of Three Test Systems: In vitro, ex vivo, and in vivo model.

From: A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumors

 

In Vitro

Animal Model

Living Test Tube

Cost Effective

+ + +

- - -

+ +

Realistically Mimic In Vivo

- - -

+ + +

+ + +

Assay Multiple Time Points

+ + +

-/+

+ + +

3 Dimensional Integration

- - -

+ + +

+ +

Real-Time Monitor

+ +

- -

+ + +

High Throughput Screening

+ + +

- - -

+ +

Ethical (Animal)

+ + +

- - -

+