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Figure 3 | Cancer Cell International

Figure 3

From: Decytabine enhances cytotoxicity induced by oxaliplatin and 5-fluorouracil in the colorectal cancer cell line Colo-205

Figure 3

Combinations of cytostatics with DNMTi agents induced changes in the cell cycle progression. DNA histograms showing cell cycle phase distribution of Colo-205 cells treated with demethylating agents, cytostatics and their combinations (in concentrations as indicated) for 72 h and determined by FACS analysis, as described in Materials and Methods. Flow cytometric profiles of DNA content upon PI staining from a representative experiment are shown. Percentages are given for each cell phase as mean ± SD (n = 4). Asterisks indicates significance at p < 0.05, for comparison with control.

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