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Figure 3 | Cancer Cell International

Figure 3

From: Dietary agent, benzyl isothiocyanate inhibits signal transducer and activator of transcription 3 phosphorylation and collaborates with sulforaphane in the growth suppression of PANC-1 cancer cells

Figure 3

Sulforpahane and BITC inhibit phosphorylation of STAT3 by IL-6. The addition of 50 ng/ml of interleukin-6 stimulates STAT3 phosphorylation in MDA-MB-453 breast cancer cells. Pre-treatment of these cells with 50 μM sulforaphane or BITC resulted in the reduction or complete abrogation of pSTAT3 respectively.

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