Figure 4From: INTS6/DICE1 inhibits growth of human androgen-independent prostate cancer cells by altering the cell cycle profile and Wnt signalingReal-time PCR of INTS6/DICE1 responsive genes. A. Up-regulation of INTS6/DICE1 expression in PC3 and DU145 cells 48 hours post-transfection with DICE1-EGFP fusion construct (DICE1) or EGFP vector (EGFP) as control. B. Selected INTS6/DICE1 responsive genes of the Wnt signaling pathway, CXX finger 4 (CXXC4), cyclin D1 (CCND1) and transcription factor 7-like 1 (TCFL1) monitored 48 hours after exogenous DICE1 expression in PC3 and DU145 cells. The fold change in gene expression was determined by the comparative C(T) method using G3PDH as reference.Back to article page