Figure 3From: Increasingly transformed MCF-10A cells have a progressively tumor-like phenotype in three-dimensional basement membrane cultureRange of morphologies observed for MCF-10CA1a cells grown in rBM for 20 days. Phase contrast micrographs of malignant MCF-10CA1a cells after 20 days in overlay three-dimensional culture which form large defined dense masses (A), more spread, less defined masses (B), highly vacuolar acini (C), and clusters of MCF-10CA1a cells that have failed to thrive in rBM (D). Scale bar, 100 μm.Back to article page