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Figure 2 | Cancer Cell International

Figure 2

From: The stimulatory activity of plasma in patients with advanced non-small cell lung cancer requires TLR-stimulating nucleic acid immunoglobulin complexes and discriminates responsiveness to chemotherapy

Figure 2

Nucleic acid and protein in plasma were required for their stimulatory activity. (A-C) PBMCs derived from normal volunteers were cultured with 20% plasma derived from NSCLC patients before treatment in the presence of the indicated dose of DNase, RNase and Papain respectively. (D and E) PBMCs derived from normal volunteers were cultured with 20% plasma derived from NSCLC patients before treatment (D) or the isolated immune complexes (IC) (E) in the presence of the of DNase (20units), RNase (5units) and Papain (20 μl) respectively. *P < 0.01. Data points represented individual patients.

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