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Table 2 Molecular characteristics of initial tumour samples

From: Astrocytoma-associated antigens - IL13Rα2, Fra-1, and EphA2 as potential markers to monitor the status of tumour-derived cell cultures in vitro

Sample TP53 EGFR amp./ch. 7 polys. EGFRvIII CDKN2A LOH 10p LOH 10q IDH1
G 108 MT Ex 8, 262, GGT → GTT A/P - DEL LOH LOH -
G 111 WT A - DEL LOH LOH -
G 112 WT A - DEL LOH LOH -
G 113 WT Low A - - ROH ROH -
G 114 WT Low A - DEL NI LOH -
  1. MT = mutation, changes in nucleotide sequences are indicated by arrows; WT = wild type; A = amplification; P = polysomy; low A = amplification at low level; DEL = deletion; LOH = loss of heterozygosity; ROH = retention of heterozygosity; NI = non informative.