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Table 5 TP 53 mutational status

From: Astrocytoma-associated antigens - IL13Rα2, Fra-1, and EphA2 as potential markers to monitor the status of tumour-derived cell cultures in vitro

Sample G108 G111 G112 G113 G114
Tumour MT ex 8, c 262, GGT → GTT WT WT WT WT
1-2 months culture MT ex 8, c 262, GGT → GTT WT WT MT ex 7; c 245 GGC → AGC MT ex 7; c 248 CGG → CAG
3-4 months culture MT ex 8,c 262, GGT → GTT WT WT MT ex 7; c 245 GGC → AGC MT ex 7; c 248 CGG → CAG
5-7 months culture MT ex 8,c 262, GGT → GTT WT WT MT ex 7; c 245 GGC → AGC n.a.
  1. MT = mutation, changes in nucleotide sequences are indicated by arrows; WT = wild type; ex = exon; c = codon; n.a. = non-analysed.