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Table 5 TP 53 mutational status

From: Astrocytoma-associated antigens - IL13Rα2, Fra-1, and EphA2 as potential markers to monitor the status of tumour-derived cell cultures in vitro

Sample

G108

G111

G112

G113

G114

Tumour

MT ex 8, c 262, GGT → GTT

WT

WT

WT

WT

1-2 months culture

MT ex 8, c 262, GGT → GTT

WT

WT

MT ex 7; c 245 GGC → AGC

MT ex 7; c 248 CGG → CAG

3-4 months culture

MT ex 8,c 262, GGT → GTT

WT

WT

MT ex 7; c 245 GGC → AGC

MT ex 7; c 248 CGG → CAG

5-7 months culture

MT ex 8,c 262, GGT → GTT

WT

WT

MT ex 7; c 245 GGC → AGC

n.a.

  1. MT = mutation, changes in nucleotide sequences are indicated by arrows; WT = wild type; ex = exon; c = codon; n.a. = non-analysed.