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Table 1 HIF-1α 1772 C > T genotype and allele frequencies in breast cancer patients and control subjects

From: SNP 1772 C > T of HIF-1α gene associates with breast cancer risk in a Taiwanese population

Parameters Breast cancer patients Control subjects pvaluea CrudeOR AdjustedORb pvalue 95% CI
Age 46.5 ± 9.9 (19-73) 44.6 ± 11.5 (21-77) 0.224     
CC (%) 53 (55%) 116 (97%)   1.00 1.00   
CT (%) 21 (22%) 0 (0%)      
TT (%) 22 (23%) 4 (3%) <0.001 12.04 11.33 <0.001 3.70-34.72
CT/CC (%) 74 (77%) 116 (97%)   1.00 1.00   
TT (%) 22 (23%) 4 (3%) <0.001 8.62 8.31 <0.001 2.74-25.25
CC (%) 53 (55%) 116 (97%)   1.00 1.00   
CT/TT (%) 43 (45%) 4 (3%) <0.001 23.53 23.23 <0.001 7.92-68.09
C genotype (%) 127 (66%) 232 (97%)   1.00 1.00   
T genotype (%) 65 (34%) 8 (3%) <0.001 14.84 14.51 <0.001 6.74-31.24
  1. aComparisons were performed by Chi-Square test.
  2. bAdjusted by age by conditional logistic regression analysis.
  3. OR = odds ratio; CI = Confidence interval.