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Table 1 HIF-1α 1772 C > T genotype and allele frequencies in breast cancer patients and control subjects

From: SNP 1772 C > T of HIF-1α gene associates with breast cancer risk in a Taiwanese population

Parameters

Breast cancer patients

Control subjects

pvaluea

CrudeOR

AdjustedORb

pvalue

95% CI

Age

46.5 ± 9.9 (19-73)

44.6 ± 11.5 (21-77)

0.224

    

CC (%)

53 (55%)

116 (97%)

 

1.00

1.00

  

CT (%)

21 (22%)

0 (0%)

     

TT (%)

22 (23%)

4 (3%)

<0.001

12.04

11.33

<0.001

3.70-34.72

CT/CC (%)

74 (77%)

116 (97%)

 

1.00

1.00

  

TT (%)

22 (23%)

4 (3%)

<0.001

8.62

8.31

<0.001

2.74-25.25

CC (%)

53 (55%)

116 (97%)

 

1.00

1.00

  

CT/TT (%)

43 (45%)

4 (3%)

<0.001

23.53

23.23

<0.001

7.92-68.09

C genotype (%)

127 (66%)

232 (97%)

 

1.00

1.00

  

T genotype (%)

65 (34%)

8 (3%)

<0.001

14.84

14.51

<0.001

6.74-31.24

  1. aComparisons were performed by Chi-Square test.
  2. bAdjusted by age by conditional logistic regression analysis.
  3. OR = odds ratio; CI = Confidence interval.