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Table 3 Multivariate analysis of the risk factors on disease-free and overall survival in the 96 breast cancer patients

From: SNP 1772 C > T of HIF-1α gene associates with breast cancer risk in a Taiwanese population

Variablea SE pvalueb Exp. (B) 95% CI of Exp. (B)
Disease-free survival time      
 Age 0.0253 0.1280 0.9622 0.9156 ~1.0112
 1772 C > T genotype 0.2715 0.3527 1.2871 0.7559 ~2.1913
 T-stage 0.4033 0.0001 4.7270 2.1445 ~10.4196
 N-stage 0.5291 0.9816 1.0122 0.3588 ~2.8554
 Microvessel density 0.4877 0.0493 2.6082 1.0028 ~6.7837
 VEGF expression 0.5858 0.2901 1.8584 0.5895 ~5.8587
 HIF-1α expression 0.4346 0.0732 2.1784 0.9294 ~5.1059
Overall survival time      
 Age 0.022 0.4883 0.9846 0.9422 ~1.0288
 1772 C > T genotype 0.300 0.5908 0.8508 0.4722 ~1.5330
 T-stage 0.446 0.0017 4.0350 1.6850 ~9.6624
 N-stage 0.589 0.8594 1.1099 0.3502 ~3.5181
 Microvessel density 0.646 0.0052 6.0924 1.7175 ~21.6115
 VEGF expression 0.610 0.9791 0.9841 0.2979 ~3.2517
 HIF-1α expression 0.481 0.3225 1.6094 0.6269 ~4.1315
  1. aby Cox regression. SE, standard error; Exp. (B), exponent (B); CI, confidence interval.
  2. bBold numbers indicate significance.