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Table 2 AURKA polymorphisms genotype distribution and allele frequency in cases and controls

From: Association between genetic polymorphisms in AURKA (rs2273535 and rs1047972) and breast cancer risk: a meta-analysis involving 37,221 subjects

First author Genotype (N) Allele frequency (N) MAF (Case/Control)
Case Control Case Control
Total AA Aa aa Total AA Aa aa A a A a
rs2273535 (T > A)
Ruan 2011 1334 599 568 167 1568 716 691 161 1766 902 2123 1013 0.34/0.32
Shi 2011 763 27 222 514 1516 71 478 967 276 1250 620 2412 0.82/0.80
MARIE-GENICA 2010 3076 1873 1096 107 5466 3290 1927 249 4842 1310 8507 2425 0.21/0.22
Couch 2007 3884 3696 188 3303 3128 175 - - - - -
Tchatchou 2007 727 37 257 433 819 47 287 485 331 1123 381 1257 0.77/0.77
Vidarsdottir 2007 759 429 288 42 653 401 231 21 1146 372 1033 273 0.25/0.21
Cox 2006 1241 774 401 66 1711 1075 571 65 1949 533 2721 701 0.22/0.21
Fletcher 2006 507 335 154 18 875 547 280 48 824 190 1374 376 0.19/0.22
Ewart-Toland 2005 898 533 303 62 448 279 148 21 1369 427 706 190 0.24/0.21
Lo 2005 707 71 288 348 1969 196 887 886 430 984 1279 2659 0.70/0.68
Dai 2004 1102 121 491 490 1186 149 503 534 733 1471 801 1571 0.67/0.66
Egan 2004 940 559 331 50 830 516 283 31 1449 431 1315 345 0.23/0.21
Sun 2004 520 50 214 256 520 66 262 192 314 726 394 646 0.70/0.62
rs1047972 (G > A)
MARIE-GENICA 2010 3139 2220 850 69 5469 3737 1561 171 5290 988 9035 1903 0.16/0.17
Cox 2006 1240 870 342 28 1724 1215 462 47 2082 398 2892 556 0.16/0.16
Lo 2005 704 543 146 15 1950 1506 414 30 1232 176 3426 474 0.13/0.12
Dai 2004 1102 805 281 16 1188 908 263 17 1891 313 2079 297 0.14/0.13
Egan 2004 905 637 245 23 788 542 225 21 1519 291 1309 267 0.16/0.17
  1. A represents the major allele, a represents the minor allele. MAF: minor allele frequencies.