Table 3 Meta-analysis results
Comparisons | OR | 95%CI | Pvalue | Heterogeneity | Effects model | |
|---|---|---|---|---|---|---|
I2 | Pvalue | |||||
a vs A | ||||||
rs2273535 | 1.08 | 1.01-1.15 | 0.02 | 62% | 0.002 | R |
Caucasian | 1.05 | 0.96-1.14 | 0.31 | 63% | 0.01 | R |
Asian | 1.12 | 1.00-1.26 | 0.04 | 66% | 0.03 | R |
rs1047972 | 0.98 | 0.89-1.08 | 0.75 | 55% | 0.06 | R |
Caucasian | 0.92 | 0.86-0.98 | 0.01 | 0% | 0.38 | F |
Asian | 1.10 | 0.97-1.25 | 0.14 | 0% | 0.37 | F |
aa vs AA | ||||||
rs2273535 | 1.36 | 1.06-1.73 | <0.00001 | 82% | <0.00001 | R |
Caucasian | 1.32 | 0.85-2.03 | 0.21 | 88% | <0.00001 | R |
Asian | 1.22 | 1.06-1.41 | 0.007 | 24% | 0.27 | F |
rs1047972 | 0.81 | 0.66-0.99 | 0.04 | 22% | 0.28 | F |
Caucasian | 0.74 | 0.59-0.93 | 0.009 | 0% | 0.56 | F |
Asian | 1.22 | 0.77-1.95 | 0.40 | 0% | 0.57 | F |
Aa vs AA | ||||||
rs2273535 | 1.02 | 0.96-1.08 | 0.52 | 0% | 0.83 | F |
Caucasian | 1.02 | 0.95-1.09 | 0.64 | 0% | 0.67 | F |
Asian | 1.02 | 0.90-1.14 | 0.80 | 0% | 0.49 | F |
rs1047972 | 0.98 | 0.91-1.05 | 0.51 | 41% | 0.14 | F |
Caucasian | 0.94 | 0.87-1.02 | 0.15 | 0% | 0.46 | F |
Asian | 1.10 | 0.95-1.26 | 0.20 | 51% | 0.15 | F |
Aa + aa vs AA | ||||||
rs2273535 | 1.04 | 0.98-1.09 | 0.20 | 12% | 0.33 | F |
Caucasian | 1.02 | 0.95-1.08 | 0.61 | 31% | 0.19 | F |
Asian | 1.07 | 0.96-1.20 | 0.21 | 0% | 0.48 | F |
rs1047972 | 0.99 | 0.89-1.10 | 0.84 | 51% | 0.09 | R |
Caucasian | 0.92 | 0.86-1.00 | 0.04 | 0% | 0.40 | F |
Asian | 1.10 | 0.96-1.27 | 0.16 | 33% | 0.22 | F |
aa vs AA + Aa | ||||||
rs2273535 | 1.15 | 1.01-1.31 | 0.04 | 69% | 0.0001 | R |
Caucasian | 1.13 | 0.92-1.38 | 0.24 | 66% | 0.007 | R |
Asian | 1.23 | 1.10-1.50 | 0.05 | 76% | 0.006 | R |
rs1047972 | 0.82 | 0.67-1.00 | 0.05 | 14% | 0.33 | F |
Caucasian | 0.75 | 0.60-0.94 | 0.01 | 0% | 0.60 | F |
Asian | 1.20 | 0.75-1.91 | 0.44 | 0% | 0.50 | F |