Array CGH was used to determine chromosomal changes in the DCIS cell lines and digitally constructed karyograms are shown. Loss of heterozygosity (LOH) is shown in purple (first column on the right of the chromosome). Red dots indicate loss and blue dots indicate gain of chromosomal materials (second and third columns on the right of the chromosome, respectively). Chromosomes are arranged from left to right (chromosomes 1 to 12 on the first row, chromosomes 13 to X on the second row). Blue boxes indicate chromosome Y which are not present in these cell lines.