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Table 1 Array CGH was performed to determine chromosomal changes in the DCIS cell lines

From: Characterization of ductal carcinoma in situ cell lines established from breast tumor of a Singapore Chinese patient

No. Gene ETCC001 ETCC006 ETCC007 ETCC008 ETCC010 ETCC011 Location
1 ABL1 - - - - - - 9q34.1
2 ABL2 - - - - - - 1q24-q25
3 ALPK2 - - - Loss(1) - - 18q21.31q
4 APC - Gain(3) Gain(3) - - Gain(3) 5q21-q22
5 ATM - - - - - - 11q22.3
6 BCR - - - - - - 22q11.21
7 BMPR1A - - - - - - 10q22.3
8 BRAF - - - - - - 7q34
9 BRCA1 - - CNLOH - CNLOH CNLOH 17q21
10 BRCA2 - - - - - - 13q12.3
11 CDK4 - - - - - - 12q14
12 CDKN2A - - - - - - 9p21
13 CHEK2 - - - - - - 22q12.1
14 CREBBP - - - - - Gain(3) 16p13.3
15 CTNNB1 - - - - - - 3p21
16 CTNNBIP1 - - - - - - 1pter-p36.31
17 EGFR - - - - - - 7p12
18 EIF4E - - - - - - 4q21-q21
19 EP300 - - - - - - 22q13
20 ERBB2 - - CNLOH - - CNLOH 17q21.1
21 ETV6 - - - - - - 12q13
22 FGFR1 CNLOH CNLOH CNLOH CNLOH - CNLOH 8p11.2-p11.1
23 FGFR2 - - - - - - 10q26
24 FGFR3 - - - - - - 4p16.3
25 FHIT - - - - - - 3p14.2
26 FLT3 - - - - - - 13q12
27 HRAS - - - - - - 11p15.5
28 KIT - - - - - - 4q11-q12
29 KRAS2 - - - - - - 12p12.1
30 MAP2K4 - Loss(1)/LOH CNLOH - CNLOH CNLOH 17p11.2
31 MAPK11 - - - - - - 22q13.33
32 MAPK12 - - - - - - 22q13.3
33 MAPK13 - - - - - - 6p21
34 MAPK14 - - - - - - 6p21.3-p21.2
35 MET - - - - - - 7q31
36 MLL - - - - - - 11q23
37 MTOR - - - - - - 1p36
38 MYC - - - - - - 8q24.12-q24.13
39 MYST3 - - - - - - 8p11
40 NRAS - - - - - - 1p13.2
41 NTRK1 - - - - - CNLOH 14q21-q22
42 NTRK3 - - - - - - 15q24-q25
43 PAX8 - Loss(1) - Loss9(1) - - 2q12-q14
44 PDGFRA - - - - - - 4q12
45 PIK3C2G - - - - - - 12p12
46 PIK3CA - - - - - - 3q26.3
47 PIP - - - - - - 7q34
48 PPARG - - - - - - 3p25
49 PRCC - - - - - CNLOH 1q21.1
50 PRKA1A - - CNLOH   CNLOH CNLOH 17q23-q24
51 PRKCB - - - - - Gain(3) 16p12
52 PTEN - - - - - - 10q23.3
53 RB1 - - - - - - 13q14.2
54 RET - - - - - - 10q11.2
55 SMAD4 - - - - - - 18q21.1
56 SCGB2A2 - - - - - - 11q13
57 SCGB2A1 - - - - - - 11q13
58 STK11 - - - - - - 19p13.3
59 TCF4 - - - - - - 18q21.1
60 TERT - Gain(3) Gain(3) - - Gain(3) 5p15.33
61 TFF1 - - - - - - 21q22.3
62 TP53 Loss(1) Loss(1)/LOH CNLOH - Loss(1)/LOH CNLOH 17p13.1
63 VHL - - - - - - 3p25.3
64 WWOX - - - - - - 16q23.3-q24.1
  1. Genetic changes in selected cancer causal genes are shown. Numbers in parentheses represent copy number of the gene. CNLOH: copy number neutral loss of heterozygosity.