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Figure 5 | Cancer Cell International

Figure 5

From: MicroRNA-492 expression promotes the progression of hepatic cancer by targeting PTEN

Figure 5

Upregulation of miR-492 and downregulation of PTEN expression is associated with poorer survival of HCC patients . (A) Scatter plot represents the statistically significant correlation in the relative transcript expression of miR-492 and PTEN (p < 0.001) in the tumor versus paired adjacent non-tumor tissues from 28 HCC patients. Each spot represents data from one HCC patient presented in the Log2 scale and the linear regression line is marked as the solid line. (B) Kaplan-Meier survival curve for HCC patients classified based on whether HCC tumor showed miR-492 upregulation (more than 2 fold) and PTEN downregulation (more than 1.5 fold), compared to the paired adjacent non-tumor samples. Upregulation of miR-492 and downregulation of PTEN expression is significantly associated with poorer patient survival (p <0.05).

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