Figure 2

Percentages of memory subsets of CD8+ T cells in control, HPV-I, and CIN-I groups. CCR7+ and CD45RA + memory subpopulations were classified as follows: A) Naive: CCR7 + CD45RA^bright; B) Central memory: CM CCR7 + CD45RA ^null/dim; C) Effector memory RA^bright: EMRA^bright, CCR7–CD45RA+, or terminally differentiated effector; D) RA^null/dim: EMRA^null/dim CCR7–CD45RA±, and E) RA– : EMRA^null CCR7–CD45RA–. By Analysis of variance (ANOVA) testing, we found a statistically significant difference between the percentages of naive, CM, and EMRA ^null/dim CD8+ T cells in the CIN-I group compared with the control group (p <0.01). CM CD8+ T cells were diminished in the HPV-I group compared with those of the control group (p <0.01).