Figure 1From: Upregulation of death receptor 5 and activation of caspase 8/3 play a critical role in ergosterol peroxide induced apoptosis in DU 145 prostate cancer cellsCytotoxic effect of EP against DU 145 prostate cancer cells. The cells were treated with various concentrations of EP (0, 25, 50, 100, and 200 μM/mL) for 72 h. Then MTT assay was carried out. (a) Chemical structure of EP. (b) Cytotoxicity of EP in DU 145, PC 3 or M2182 prostate cancer cells and (c) HCT116 colon cancer cells, A549 lung cancer cells, SKOV3 ovary cancer cells, and (d) RWPE1 (prostate epithelial cells). Data are presented as means ± S.D of triplicate samples.Back to article page