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Figure 5 | Cancer Cell International

Figure 5

From: Upregulation of death receptor 5 and activation of caspase 8/3 play a critical role in ergosterol peroxide induced apoptosis in DU 145 prostate cancer cells

Figure 5

Effect of siRNA DR 5 transfection on PARP and procaspase 8 in EP treated DU 145 prostate cancer cells. (a) Western blot assay was carried out with indicated antibodies to see the expression of FLIP, FADD, DR 5 or DR 4 in EP treated DU 145 cells. (b) After transfection with siRNA DR 5, EP was treated and incubated in DU 145 cells for 24 h. The lysates were subjected to western blot analysis using DR 5, PARP, procaspase 8 or β-actin antibodies. Bar graph represents the relative expression of the DR 5 protein by using images J software.

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