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Table 2 Incidence rate of MSI and LOH, number of alleles isolated, and allelic imbalance noticed for each marker

From: Chemotherapy induced microsatellite instability and loss of heterozygosity in chromosomes 2, 5, 10, and 17 in solid tumor patients

Marker

Chr./Locus

No of positive patients

% of positive MSI

No. of alleles isolated

Allelic imbalance

Mfd15

17q11.2

15

19.2%

7

L 0–0.69 U 1.56-2.72

APC

5q21/22

17

21.8%

8

L 0–0.69 U 1.5-2.61

Tp53-Alu

17p13.1

27

34.6%

12

L 0–0.67 U 1.48-2.53

Mfd41

17p12-11.1

21

26.9%

8

L 0–0.59 U 1.35-2.76

Bat-25

4q12

0

0%

4

L 0.71-0.77 U 0.94-1.2

TP53.PCR15

17p13.1

0

0%

5

L 0.80-0.86 U 0.92-1.23

AFM093xh3

2p16

11

14.1%

6

L 0–0.68 U 1.51-2.44

Bat-40

1p13.1

0

0%

4

L 0.73-0.81 U 0.91-1.31

Bat-26

2p

3

3.8%

4

L 0.23-0.62 U 1.31-1.65

Mfd28

10pter

7

8.9%

5

L 0.2-0.64 U 1.37-1.95

  1. L = lower allelic imbalance. U = upper allelic imbalance range.