Figure 8

Acidic pH _e induces migration activity. Confluent cultures were scratched with micropipette tips and further cultured in 2% serum-containing medium adjusted to pH 7.4 or 6.8. Photographs were taken and cell migration was measured. A. Phase contrast micrograph. B. Migrated distance relative to LLCm1 cells at pH 7.4. Representative results were shown from three independent experiments (n = 8). *P < 0.05; **P < 0.01. C. Relative numbers of invasive cells compared with LLCm1 cells at pH 7.4.” between “B. Migrated distance relative to LLCm1 cells at pH 7.4.” and “Representative results were shown from three independent experiments (n = 8).