Skip to main content

Table 2 Characteristics of studies included in the meta-analysis

From: EGF +61A/G polymorphism contributes to increased gastric cancer risk: evidence from a meta-analysis

First author (Year)

Country

Ethnicity

Sample size (case/control)

Genotyping methods

Matching criteria

Source of control

GC ascertainment

Quality scores

HWE (Pvalue)

Hamai 2004

Japan

Asian

200/230

PCR-RFLP

Age, sex, and H. pylori infection

HB

NR

5.5

0.647

Goto 2005

Japan

Asian

202/450

PCR-CTPP

NR

PB

Pathologically confirmed

6.5

0.537

Jin 2007

China

Asian

617/660

PCR-RFLP

Age, sex, smoking and drinking

PB

Histopathologically confirmed

7.0

0.407

Araujo 2011

Portugal

Caucasian

207/984

PCR-RFLP

NR

HB

Histologically confirmed

4.5

0.010

Yang 2012

China

Asian

207/318

PCR-RFLP

Age, and sex

HB

Histologically confirmed

6.5

0.272

Lin 2012

China

Asian

114/120

PCR-RFLP

Sex

HB

Pathologically confirmed

5.0

0.485

  1. GC, Gastric cancer; NR, Not reported; PB, Population–based; HB, Hospital–based; HWE, Hardy–Weinberg equilibrium in control population; PCR–RFLP, Polymerase chain reaction-restriction fragment length polymorphism; PCR-CTPP, PCR with confronting two-pair primers; H. pylori, Helicobacter pylori.