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Table 2 Characteristics of studies included in the meta-analysis

From: EGF +61A/G polymorphism contributes to increased gastric cancer risk: evidence from a meta-analysis

First author (Year) Country Ethnicity Sample size (case/control) Genotyping methods Matching criteria Source of control GC ascertainment Quality scores HWE (Pvalue)
Hamai 2004 Japan Asian 200/230 PCR-RFLP Age, sex, and H. pylori infection HB NR 5.5 0.647
Goto 2005 Japan Asian 202/450 PCR-CTPP NR PB Pathologically confirmed 6.5 0.537
Jin 2007 China Asian 617/660 PCR-RFLP Age, sex, smoking and drinking PB Histopathologically confirmed 7.0 0.407
Araujo 2011 Portugal Caucasian 207/984 PCR-RFLP NR HB Histologically confirmed 4.5 0.010
Yang 2012 China Asian 207/318 PCR-RFLP Age, and sex HB Histologically confirmed 6.5 0.272
Lin 2012 China Asian 114/120 PCR-RFLP Sex HB Pathologically confirmed 5.0 0.485
  1. GC, Gastric cancer; NR, Not reported; PB, Population–based; HB, Hospital–based; HWE, Hardy–Weinberg equilibrium in control population; PCR–RFLP, Polymerase chain reaction-restriction fragment length polymorphism; PCR-CTPP, PCR with confronting two-pair primers; H. pylori, Helicobacter pylori.