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Figure 7 | Cancer Cell International

Figure 7

From: Hypericin-mediated photodynamic therapy induces apoptosis of myoloma SP2/0 cells depended on caspase activity in vitro

Figure 7

The effects of different caspase inhibitors on apoptosis induced by hypericin mediated PDT. SP2/0 Cells were pretreated with caspase pan inhibitor Z-VAD-FMK (100.0 μM) or caspase-3 inhibitor Ac-DEVD-CHO (100.0 μM) for 1 h, and then exposed with 0.05 μM hypericin for 16 hours. At 24 hour after 11.28 J/cm2 irradiation, apoptosis was assayed by flow cytometry after staining with PI. a: control; b: hypericin; c: hypericin + Ac-DEVD-CHO; d: hypericin + Z-VAD-FMK.

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