Figure 5From: A polymethoxyflavone from Laggera pterodonta induces apoptosis in imatinib-resistant K562R cells via activation of the intrinsic apoptosis pathwayDHTMF alone or combination of IM induces mitochondria dysfunction in K562R cells. A: Cells were stained with JC-1 dye and analyzed by flow cytometry.**, P < 0.01 vs. Control, ##, P < 0.01 vs. 1 μmol/L IM, ■■, P < 0.01 vs. 5 μg/mL DHTMF. B: DHTMF induces mitochondria dysfunction on K562R cells. Cells were analyzed with a laser confocal microscope, Bar = 20 μm.Back to article page