Figure 4From: miR-22 is down-regulated in esophageal squamous cell carcinoma and inhibits cell migration and invasionOverexpression of miR-22 inhibits migration and invasion of ESCC cell lines. (A) Overexpression of miR-22 presented a slower closing of scratch wound, compared with miRNA negative control, at 48 h after transfection in Eca109 and Kyse410 cells. (B) The inhibitory effect of miR-22 toward the invasion and migration of Eca109 and Kyse410 cells. *P < 0.05, by one-way ANOVA.Back to article page