Sch B decreases the mitochondrial membrane potential (ΔΨm) in glioma cells. U87 and U251 cells were treated with Sch B (0, 25, 50, 100 μmol/L) for 48 h. A. Flow cytometric analysis of ΔΨm by rhodamine 123 staining. B. The corresponding histogram shows the percentages of cells with high ΔΨm (survival) and low ΔΨm (apoptosis). Values represent the means ± SD (n = 3). *P < 0.05; **P < 0.01; ***P < 0.001 compared with the control group.