Sch B induces apoptosis via the regulation of apoptosis-related proteins in glioma cells. A. After treatment with Sch B (0, 25, 50, 100 μmol/L) for 48 h, cell lysates of U87 and U251 cells were prepared, and the expression of cleaved caspase-3, cleaved PARP, Bax and Bcl-2 were analysed using western blot. β-actin was used as a loading control. B. The ratio of Bcl-2 to Bax was calculated by band density. The results were shown as the mean ± SD compared with the control (designated as 1.00). *P < 0.05; **P < 0.01 compared with the control group.