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Figure 4 | Cancer Cell International

Figure 4

From: Inhibition of miR-191 contributes to radiation-resistance of two lung cancer cell lines by altering autophagy activity

Figure 4

Beclin-1 was a direct target of miR-191. (A) Schematic representation of the 39- UTR of human Beclin-1 transcript. Predicted miR-191 binding site was depicted. The numbers (+121–140) represented the nucleotides that were predicted to base pair with the miR-191 seed sequence. (B) The expression of miR-191 in radiation-resistant A549 cells with or without Beclin-1 mutation (*p <0.05 vs control, n = 3). (C) The expression of miR-191 in radiation-resistant H1299 cells with or without Beclin-1 mutation (*p <0.05 vs control, n = 3).

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