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Figure 4 | Cancer Cell International

Figure 4

From: Deguelin induces the apoptosis of lung cancer cells through regulating a ROS driven Akt pathway

Figure 4

Relative protein expression under the treatment of Deguelin. A: Gel image of Western blot analysis showing the related protein expression in NCI-1975 cells exposed to Deguelin (5 and 20 μM) with or without the presence of NAC. B: Bar graph representing the semi-quantification of gel image (p-Akt/Akt) normalizing the band with the GAPDH control. # represents p < 0.05 vs the corresponding dose between cells without and with the treatment of NAC. ** represents p < 0.01 vs the control cells. Data are presented as mean ± SD (n = 3). C: Bar graph representing the semi-quantification of gel image (p-GSK3β/GSK3β) normalizing the band with the GAPDH control. # represents p < 0.05 vs the corresponding dose between cells without and with the treatment of NAC. ** represents p < 0.01 vs the control cells. Data are presented as mean ± SD (n = 3). D: Bar graph representing the semi-quantification of gel image (Caspase-3) normalizing the band with the GAPDH control. # represents p < 0.05 vs the corresponding dose between cells without and with the treatment of NAC. ** represents p < 0.01 vs the control cells. Data are presented as mean ± SD (n = 3).

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