Figure 1

Plectin depletion enhanced Chang liver cell migration. Plectin siRNA-transfected Chang liver cells were transferred to trans-well migration insert, followed by 4 hour incubation as described in the section of “materials and methods”. Plectin-knockdown Chang liver cell (refer to as Plectin siRNA) significantly showed a higher level of cell migration. Data are presented as mean ± standard error obtained from three independent experiments, *** indicates p < 0.001. The migrated cell number of mock group was assumed as 100%. Cell migration of plectin-knockdown Chang liver cell is presented as the ratio to that of the mock group.